ABSTRACT
Background: Neonatal septicemia is the major cause of Neonatal mortality. It might be possible to reduce these deaths by early diagnosis and proper management. Objectives: (1) To find out various bacteriological agents involved in neonatal septicaemia in PDU Medical college & Hospital Rajkot (2) to findout the organisms responsible for early onset and late onset neonatal sepsis. Methods: A hospital based prospective study was carried out in 100 clinically supsected cases of neonatal septisemia in New Born Intensive Care Unit (NICU) at P.D.U Medical College & Hospital Rajkot. Results: Out of 100 neonates with clinically suspected neonatal septicemia, 62(62%) were blood culture positive. Gram negative bacteria accounted for 50(80.65%) & Gram positive bacteria accounted for 12(19.35%) of all cases. Among Gram Negative bacteria Klebsiella spp 25(40.32%) being the most common organism & Staphylococcus aureus 8(12.90%) being the most common organism among Gram Positive bacteria. Late sepsis was most commonly associated with klebsiella spp19 (41.3%).Conclusion: Neonatal septicaemia should be diagnosed urgently to reduce the mortality. Suspected infection based on clinical criteria need to supported by microbial investigation to find causative organisms and their antibiotic sensitivity pattern.
ABSTRACT
Background & objectives: Developing country like India shows high prevalence of hepatitis C on account of lack of universal precautions while treating patients. This kind of transmission is seen more in cases of Thalesemias on regular blood transfusion, with renal diseases on haemodialysis and co-infection with hepatitis B along with patients admitted in various wards for treatment. Study was conducted with the objective to find out prevalence of HCV infection in patients with hepatitis B, Thalesemias, patients undergoing haemodialysis, patients admitted in hospital for other diseases who are hepatitis B negative, Ante-natal cases and voluntary healthy blood donors. Methods: Blood was collected of 1040 persons from various groups with their consent. All the sera were tested for anti HCV antibody by ELISA and Signal HCV test. Results: Total twelve participants were found positive for HCV infection, majority were belonged to Thalesemic group and rest of the participants belonged to voluntary healthy blood donor group, patients of hepatitis B and patients on haemodialysis. Interpretation & conclusion: those who are at risk of getting Hepatitis C should undergo for HCV testing on regular interval.
ABSTRACT
Objective: Hepatitis is a major public health problem throughout the world affecting several hundred million of people. Aim is to study incidence of HIV seropositivity in blood donors and suspected patients attending voluntary council and testing centre and to compare prevalence of Anti HCV antibody positivity in HIV seropositive samples. Material and Methods: A total of 1786 serum samples were tested for HIV antibodies in patients attending Voluntary Council and Testing Centre (VCTC) at Guru Govind Singh Hospital, Jamnagar. The serum sample of HIV seropositive patients were tested for HCV antibodies. Those serum samples found positive for Anti-HCV antibody were reconfirmed by Signal HCV method. Out of total 1786 samples for HIV 297 patients were positive (16.63%) for HIV and 1489 patients were negative (83.37%) for HIV. Discussion: As the hepatitis C virus has capacity to induce chronicity that leads to cirrhosis and liver cancer in long term. In the absence of vaccine and effective chemotherapy, screening of more and more serum samples is the only way to prevent post transfusion hepatitis C virus infection.